I've been using MSD stuff on everything possible for 30 years.A 6AL box is driving my LZ-23.But electricity has it's own laws.When the voltage reaches"X",it's going to jump the gap-it doesn't matter wether the coil puts out 50K or 30 K.Spark is spark.
MSD makes some good products as i've stated,but if your system is dead nuts on MSD anything will do nothing in the way of adding HP.BUt a MSD box with a rev limiter is very cheap insurance.