Not literally, I'm talking complete imbalance of power, handling, braking, ect. The skill and fab work required for the swap, ect. I just really want you to know what you are going into. A powerful engine does not mean anything if nothing else is up to the same performance level.
If you have the budget and cash to build up this car, reinforce it with a good suspension setup, differential, ect then it will be a very very quick car, but if you do not then you will end up with a completely unusable car that wont be fun to drive.
I don't want to discourage the swap as it would be very cool, but I really just doubt how much skill, knowledge and experience you have! I'm not saying I have it, I'm saying its a long hard learning process!
I have messed around with a toyota 7MGE, just doing the headgasket its several times more complex than the Datsun L motor, I hate to see what a 1uz is like diving in with no experience. As long as you understand that, sure go ahead and try - but if you do not have anyone to help you that has the knowledge a fuel injected motor like that is going to be a complete pain.